In GTA Online, taking out vehicles effectively requires the right weapons. Here’s a list of the best options for destroying vehicles in various scenarios:

1. Heavy Sniper Mk II

Description: The Heavy Sniper Mk II is renowned for its immense damage output and long range. It can one-shot most vehicles, making it a top choice for players looking to disable or destroy enemy cars from a distance. U4GM provides gta cheap buy 5 money to help players make more efficient use of their time. Use coupon code "allen" to get 5% off at U4GM.

Special Rounds: Consider using explosive rounds to maximize damage against armored vehicles.

2. Railgun

Description: The Railgun is a powerful weapon that fires a projectile capable of destroying vehicles with a single shot. It has minimal bullet drop and is effective against both ground and airborne targets.

Availability: Often available during special events or at the Gun Van.

3. Homing Launcher

Description: This launcher is perfect for targeting moving vehicles, especially aircraft. It locks onto targets, allowing for precise shots even at long distances.

Usage: Best used against helicopters and fast-moving cars, ensuring you can hit your target with ease.

4. Sticky Bombs

Description: Sticky bombs are versatile explosives that can be attached to vehicles or thrown at targets. They are effective for ambushes and can be detonated at your discretion.

Strategy: Use them to disable enemy vehicles or set traps in high-traffic areas.

5. Grenade Launcher

Description: The Grenade Launcher is effective for taking out groups of enemies or damaging vehicles from a distance. It can be particularly useful in urban environments where cover is available.

Tip: Aim for the ground near vehicles to maximize splash damage.

6. Pump Shotgun Mk II (with Explosive Slugs)

Description: This shotgun can deal significant damage at close range, especially when loaded with explosive slugs. It's highly effective for ambushing players exiting their vehicles.

Usage: Ideal for close encounters where you need to quickly disable an enemy vehicle.

7. Mini SMG

Description: While not as powerful as other options, the Mini SMG offers a high rate of fire, making it useful for drive-bys or quick engagements against unarmored vehicles.

Best For: Close-range combat while on the move.

For taking out vehicles in GTA Online, the Heavy Sniper Mk II and Railgun stand out due to their high damage capabilities and effectiveness at range. The Homing Launcher and Sticky Bombs provide versatility in targeting moving threats, while shotguns and SMGs are excellent choices for close encounters. By equipping a mix of these weapons, players can effectively handle any vehicular threat they encounter in Los Santos.